Jurgen Klopp kept faith with Karius between the sticks at the NSC Olimpiyskiy Stadium as Liverpool targeted their first piece of silverware his Anfield reign.
But the 24-year-old will not have fond memories of his trip to Kiev as his howlers helped Real Madrid secure their third Champions League title on the spin.
Karius inexplicably threw the ball into Karim Benzema and could only watch on as it rolled into the net for Real’s opener.
And he was at fault again in the 83rd minute when he failed to deal with a long-range Gareth Bale effort which put Zinedine Zidane’s side out of sight at 3-1.
Mignolet has now revealed what he told Karius in the wake of the shocking performance, which has seen the German receive plenty of flak.
“I know how it is,” Mignolet told Sky Sports. “You need a bit of time.
“The good thing about this final is that he will have the summer to take it and go forward.
“If he wants to talk then of course I will be there. Every goalkeeper can relate to him.
“I’ve been in this situation before myself and those kind of things you deal with yourself.
“The only thing I told him is that there is a reason we got to this final, and why we played in this final, so think about that.
“But of course it is very difficult to say anything to him and to let him grasp it.
“He’s only young. I’m sure he will [bounce back].
“I think we have all the tools at Liverpool as well to help him with that.”
Mignolet also opened up about his sympathy for Liverpool fans who have supported Klopp’s men all season.
“When you see the amount of supporters who were behind us throughout the whole campaign, with their special songs, they made something special happen this year,” the Belgian added.
“It’s very bitter that we can’t give them something back and not to give them the trophy that they wanted.
“Together with the fans, together with the rest of the club. I think we play not as individuals, but as a team, we play as 11 together, we play as a whole squad.
“Everyone was behind the team from the very first moment we stepped into the Champions League and I think that will be the same going forward.
“Liverpool stands for unity, Liverpool stands for ‘all together’. I think that will not only be the right ideal for Liverpool, it has always been their history and will always be their future.”