Julian Castillo, 26, took two months and used 2.5 litres of blood from 12 different donors to create the bloody mural.
The tattoo artist from Roldanillo, Colombia, created the mural at the School of Belisario Pena Pinero in an attempt to make a statement against “innocent blood being shed”.
He also did it in favour of building a society that was “free of oppression and injustice”, following a national student strike in the city of Cali.
In the video, Julian pours the deep red blood from a bottle into a plastic cup.
He then stands next to the art that measures almost twice the height of him.
In another clip, the artist can be seen painting the blood onto the mustard-coloured backdrop using a long brush.
Julian later said: “I thought people would react badly to my artwork, for using blood as a material, but actually a lot of people liked it.
“It was like a sociological experiment and after everything was done, people thought it was a great job.”
He mixed the blood with tattoo ink and acrylic paint and entitled it Blood Mural 2.0.
Julian is now hoping the Guinness World Records will agree to list the mural as the largest ever painted using human blood – following him being recognised by them two years ago for creating the world’s largest ever mural using only pencils.
He added: “We have registered the artwork with Guinness World Records but it has not yet been confirmed by them.”
Since posting an image of the art online, scores of people have flooded in to comment on the bloody art.
One person said: “What you do cannot go unnoticed, and the important thing is the good name of Roldanillo as a cultural and artistic epicentre.”
Another added: “What I like most is that thanks to you, we’re seeing positive news about Roldanillo.
“Not like in other times when it was only mentioned for bad things. Thanks a lot.”
It comes after a beer can collector has proudly revealed that he is Britain’s Dullest Man.