The second instalment of one of boxing’s most heated rivalries takes place at the T-Mobile Arena in Las Vegas in the early hours of Sunday morning UK time.
Golovkin will defend his WBA and WBC middleweight belts in a rematch that was initially supposed to take place on May 5, but was thrown into jeopardy after Canelo failed a drugs test back in February.
Both fighters made the division limit of 159.6lbs for the rematch – Alvarez tipping the scales at 159.4lbs with Golovkin two pounds heavier.
However, the traditional face-off following the weigh-in was ugly as Canelo rushed at his rival.
Canelo tried to push his forehand into his opponent, but Golovkin stood there motionless.
After 15 seconds, the pair had to be restrained before things could spill over even further.
Golden Boy president Eric Gomez, who promotes Alvarez, believes his man has Golovkin running scared.
“They’re coming up with everything you can imagine,” he said.
“They’re complaining about Canelo’s beard.
“They have complained about the tape.
“They complained about the judges and the referee.
“What that shows me is, they’re worried.
“Every time, they’ve gotten what they wanted, and that’s okay, because we have the better fighter and if they have gotten all of these rulings the way they want, there can be no excuses when Canelo beats him.”
Golovkin, who has yet to lose in 39 boxing bouts, goes in as the slight favourite.
Meanwhile, former unified light-welterweight champion Amir Khan believes the bout shouldn’t be going ahead.
He said: “This fight shouldn’t even be happening.
“They should have fined him big time and used him as an example.
“You’re going into a ring to beat someone up — you can literally kill someone. If you’ve got all the drugs in your body, you can kill someone. I can’t believe they let fighters go on.
“People have forgotten about it. Nobody has really talked about it. We want boxing to be a good, clean sport and to be respected.”